abstract：:Early life events have special importance in the development as postnatal environmental alterations may permanently affect the lifetime vulnerability to diseases. For the interpretation of the long-term consequences it is important to understand the immediate effects. As the role of vasopressin in hypothalamic-pituita...

journal_title：Psychoneuroendocrinology

authors： Zelena D,Stocker B,Barna I,Tóth ZE,Makara GB

更新日期：2015-01-01 00:00:00

abstract：:Previous studies have shown that strength exercise improves memory and increases expression of a myriad of proteins involved on neuronal survival and synaptic plasticity in the hippocampus. Conversely, chronic exposure to supraphysiological levels of anabolic androgenic steroids (AAS) can induce psychiatric abnormalit...

journal_title：Psychoneuroendocrinology

authors： Novaes Gomes FG,Fernandes J,Vannucci Campos D,Cassilhas RC,Viana GM,D'Almeida V,de Moraes Rêgo MK,Buainain PI,Cavalheiro EA,Arida RM

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Posttraumatic stress disorder (PTSD) is associated with a 2-4 fold increased risk of developing Type 2 diabetes mellitus. However, detailed assessments of glucose metabolism and insulin secretion in a study designed to minimize confounders are lacking. Furthermore, few studies examine potential mechanisms in...

journal_title：Psychoneuroendocrinology

authors： Rao MN,Chau A,Madden E,Inslicht S,Talbot L,Richards A,O'Donovan A,Ruoff L,Grunfeld C,Neylan TC

更新日期：2014-11-01 00:00:00

abstract：:A wealth of evidence has linked individual differences in testosterone (T) to social, cognitive, and behavioral processes related to human dominance. Moreover, recent evidence indicates that a single administration of T reduces interpersonal trust in healthy young women. Here, in a sample of men and women (n=96), we i...

journal_title：Psychoneuroendocrinology

authors： Carré JM,Baird-Rowe CD,Hariri AR

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Adult offspring of Holocaust survivors comprise an informative cohort in which to study intergenerational transmission of the effects of trauma exposure. Lower cortisol and enhanced glucocorticoid sensitivity have been previously demonstrated in Holocaust survivors with PTSD, and in offspring of Holocaust su...

journal_title：Psychoneuroendocrinology

authors： Bierer LM,Bader HN,Daskalakis NP,Lehrner AL,Makotkine I,Seckl JR,Yehuda R

更新日期：2014-10-01 00:00:00

abstract：:A number of studies have now examined the association between smoking and the magnitude of physiological reactions to acute psychological stress. However, no large-scale study has demonstrated this association incorporating neuroendocrine in addition to cardiovascular reactions to stress. The present study compared ne...

journal_title：Psychoneuroendocrinology

authors： Ginty AT,Jones A,Carroll D,Roseboom TJ,Phillips AC,Painter R,de Rooij SR

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Maternal smoking during pregnancy (MSDP) is associated with early and long-term neurobehavioral deficits; however mechanisms remain unknown. We tested the hypothesis that MSDP programs the hypothalamic pituitary adrenocortical (HPA) axis of the offspring leading to adverse outcomes. In an intensive, prospect...

journal_title：Psychoneuroendocrinology

authors： Stroud LR,Papandonatos GD,Rodriguez D,McCallum M,Salisbury AL,Phipps MG,Lester B,Huestis MA,Niaura R,Padbury JF,Marsit CJ

更新日期：2014-10-01 00:00:00

abstract：:In many species testosterone fluctuates in concert with outcome-dependent changes in social status, such that winning a competition leads to an increase in circulating testosterone (i.e., competition effect). Although this phenomenon has been well studied in humans, the cumulative endocrine impact of multiple successi...

journal_title：Psychoneuroendocrinology

authors： Zilioli S,Watson NV

更新日期：2014-09-01 00:00:00

abstract：:Research has suggested that stressful situations lead to a decrease in testosterone, whereas concern with one's social status increases testosterone. However, results from studies examining testosterone reactivity in stressful situations that involve evaluation by others (hence status concerns) are inconsistent. Furth...

journal_title：Psychoneuroendocrinology

authors： Bedgood D,Boggiano MM,Turan B

更新日期：2014-09-01 00:00:00

abstract：:Brain oxytocin and dopamine systems interact to modulate social cognitive behavior. Whether the interactions are modulated by oxytocin receptor (OXTR) gene variations remains unclear. Considering the dopamine transporter (DAT) availability as an endophenotype and the degree of dopamine-mediated neuroticism as a phenot...

journal_title：Psychoneuroendocrinology

authors： Chang WH,Lee IH,Chen KC,Chi MH,Chiu NT,Yao WJ,Lu RB,Yang YK,Chen PS

更新日期：2014-09-01 00:00:00

abstract：:Several lines of evidences suggest that the brain-derived neutrophic factor (BDNF) is implicated in the pathophysiology of depression. However, the molecular mechanisms are not fully understood. In the current study we aimed to investigate how genetic modulation of BDNF in the hippocampus using microRNa124a (miR124a)-...

journal_title：Psychoneuroendocrinology

authors： Bahi A,Chandrasekar V,Dreyer JL

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Heterogeneous hypothalamo-pituitary-adrenal (HPA) system dysregulation has been shown in multiple sclerosis (MS), and cross-sectional studies suggested increasing hyperactivity with longer, progressing disease. Longitudinal studies to confirm this hypothesis and to study the impact of disease modifying treat...

journal_title：Psychoneuroendocrinology

authors： Kümpfel T,Schwan M,Weber F,Holsboer F,Trenkwalder C,Then Bergh F

更新日期：2014-07-01 00:00:00

abstract：:Stress disorders are among the most commonly occurring of all mental disorders. In this context, the question arises whether the stress inevitably unfolding around us has the potential to "contaminate" and compromise us. In the current multi-center study, we investigate the existence of such empathic stress (defined a...

journal_title：Psychoneuroendocrinology

authors： Engert V,Plessow F,Miller R,Kirschbaum C,Singer T

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The hypothalamic-pituitary-adrenal (HPA) axis is a critical mediator linking stress to health. Understanding how to modulate its reactivity could potentially help reduce the detrimental health effects of HPA axis activation. Social evaluative threat is a potent activator of this system. Access to control and...

journal_title：Psychoneuroendocrinology

authors： Abelson JL,Erickson TM,Mayer SE,Crocker J,Briggs H,Lopez-Duran NL,Liberzon I

更新日期：2014-06-01 00:00:00

abstract：:Emerging research has suggested that hormone treatments such as selective oestrogen receptor modulators (SERMs) or progestins may be useful in the treatment of mania. The current pilot study compared the use of the SERM tamoxifen and the progestin medroxyprogesterone acetate (MPA), as an adjunct to mood stabiliser med...

journal_title：Psychoneuroendocrinology

authors： Kulkarni J,Berk M,Wang W,Mu L,Scarr E,Van Rheenen TE,Worsley R,Gurvich C,Gavrilidis E,de Castella A,Fitzgerald P,Davis SR

更新日期：2014-05-01 00:00:00

abstract：:The enzyme telomerase, through its influence on telomere length, is associated with health and mortality. Four pioneering randomized control trials, including a total of 190 participants, provided information on the effect of mindfulness meditation on telomerase. A meta-analytic effect size of d=0.46 indicated that mi...

journal_title：Psychoneuroendocrinology

authors： Schutte NS,Malouff JM

更新日期：2014-04-01 00:00:00

abstract：:Sensitization is defined as a non-associative learning process occurring when repeated administrations of a stimulus result in a progressive amplification of a response (Shettleworth, 2010). The purpose of this review paper is to discuss whether brain sensitization is helpful in common health problems in man. The pape...

journal_title：Psychoneuroendocrinology

authors： Ursin H

更新日期：2014-04-01 00:00:00

abstract：:The stress hormone cortisol reduces retrieval of emotional memories, which has been suggested to support the treatment of psychiatric disorders characterized by exaggerated fear-related memories. Indeed, studies in patients with anxiety disorders have indicated that the success of exposure therapy can be enhanced with...

journal_title：Psychoneuroendocrinology

authors： Merz CJ,Hamacher-Dang TC,Wolf OT

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Leptin (LEP) is a hormone central for energy homeostasis and has been implicated in neurodevelopment. This adipokine is produced by the placenta and is epigenetically regulated by promoter DNA methylation. Recent evidence has suggested a role for LEP in behavioral development. In this study, we investigated ...

journal_title：Psychoneuroendocrinology

authors： Lesseur C,Armstrong DA,Murphy MA,Appleton AA,Koestler DC,Paquette AG,Lester BM,Marsit CJ

更新日期：2014-02-01 00:00:00

abstract：:The current study investigates the effect of a single episode of acute social stress on healthy children's processing of facial expressions of emotion. Healthy nine- and ten-year-old boys (N=39) underwent either a standardized psychosocial laboratory stressor (the Trier Social Stress Test for Children) or a control co...

journal_title：Psychoneuroendocrinology

authors： Chen FS,Schmitz J,Domes G,Tuschen-Caffier B,Heinrichs M

更新日期：2014-02-01 00:00:00

abstract：:Substantial research has been conducted investigating the association between life adversity and genetic vulnerability for depression, but clear mechanistic links are rarely identified and investigation often focused on single genetic variants. Complex phenotypes like depression, however, are likely determined by mult...

journal_title：Psychoneuroendocrinology

authors： Vogel S,Gerritsen L,van Oostrom I,Arias-Vásquez A,Rijpkema M,Joëls M,Franke B,Tendolkar I,Fernández G

更新日期：2014-02-01 00:00:00

abstract：:Interpersonal touch is frequently used for communicating emotions, strengthen social bonds and to give others pleasure. The neuropeptide oxytocin increases social interest, improves recognition of others' emotions, and it is released during touch. Here, we investigated how oxytocin and gentle human touch affect social...

journal_title：Psychoneuroendocrinology

authors： Ellingsen DM,Wessberg J,Chelnokova O,Olausson H,Laeng B,Leknes S

更新日期：2014-01-01 00:00:00

abstract：:Stress is thought to alter motivational processes by increasing dopamine (DA) secretion in the brain's "reward system", and its key region, the nucleus accumbens (NAcc). However, stress studies using functional magnetic resonance imaging (fMRI), mainly found evidence for stress-induced decreases in NAcc responsiveness...

journal_title：Psychoneuroendocrinology

authors： Oei NYL,Both S,van Heemst D,van der Grond J

更新日期：2014-01-01 00:00:00

abstract：:The nature of hormonal involvement in pubertal brain development has attracted wide interest. Structural changes within the brain that occur during pubertal development appear mainly in regions closely linked with emotion, motivation and cognitive functions. Using a sheep model, we have previously shown that peri-pube...

journal_title：Psychoneuroendocrinology

authors： Nuruddin S,Krogenæs A,Brynildsrud OB,Verhaegen S,Evans NP,Robinson JE,Haraldsen IR,Ropstad E

更新日期：2013-12-01 00:00:00

abstract：:Antidepressants affect glucocorticoid receptor (GR) functioning partly through modulation of its phosphorylation but their effects on mitochondrial GR have remained undefined. We investigated the ability of chronic fluoxetine treatment to affect chronic stress-induced changes of mitochondrial GR and its phosphoisoform...

journal_title：Psychoneuroendocrinology

authors： Adzic M,Lukic I,Mitic M,Djordjevic J,Elaković I,Djordjevic A,Krstic-Demonacos M,Matić G,Radojcic M

更新日期：2013-12-01 00:00:00

abstract：:Recent cross-species research has demonstrated that the neurohormone oxytocin plays a key role in social interaction and cognitive processing of others' emotions. Whereas oxytocin has been shown to influence social approach, trust, and bond formation, a potential role of the oxytocinergic system in blurring or enhanci...

journal_title：Psychoneuroendocrinology

authors： Colonnello V,Chen FS,Panksepp J,Heinrichs M

更新日期：2013-12-01 00:00:00

abstract：:Salivary cortisol and alpha-amylase are known to have distinctive diurnal profiles. However, little is known about systematic changes in these biomarkers across the adult lifespan. In a study of 185 participants (aged 20-81 years), time-stamped salivary cortisol and alpha-amylase were collected 7 times/day over 10 day...

journal_title：Psychoneuroendocrinology

authors： Nater UM,Hoppmann CA,Scott SB

更新日期：2013-12-01 00:00:00

abstract：:The role of opioid receptors in infant-mother attachment has been well established. Morphine, a preferential μ opioid receptor (MOR) agonist, attenuates separation distress vocalizations and decreases physical contact between infant and mother. However, there is little research on how opioid receptors are involved in ...

journal_title：Psychoneuroendocrinology

authors： Ragen BJ,Maninger N,Mendoza SP,Jarcho MR,Bales KL

更新日期：2013-11-01 00:00:00

abstract：:Sumoylation is a recently described post-translational modification and only a few sumoylated neurotransmitter receptors are known. Through the present studies, we discovered that serotonin1A receptors (5-HT1A-Rs) can be sumoylated by SUMO1 (small-ubiquitin-related modifier 1) protein. The SUMO1-5-HT1A-R is ∼55kDa, is...

journal_title：Psychoneuroendocrinology

authors： Li Q,Muma NA

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Childhood adversities are known to be associated with poorer health outcomes. A potential mechanism may be through changes in inflammatory processes. One such childhood adversity is separation of parents, however relatively little is known about the association between parental separation and inflammation in...

journal_title：Psychoneuroendocrinology

authors： Lacey RE,Kumari M,McMunn A

更新日期：2013-11-01 00:00:00

abstract：:Testosterone concentrations rise rapidly in the context of competitive interactions and remain elevated in winners relative to losers. Theoretical models suggest that this divergent neuroendocrine response serves to mediate future dominance behaviours. Although research in animal models provides compelling support for...

journal_title：Psychoneuroendocrinology

authors： Carré JM,Campbell JA,Lozoya E,Goetz SM,Welker KM

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Sex differences in levels of C-reactive protein (CRP) are well established in adulthood, but little is known about when and why they emerge. Here, we tested longitudinal models of CRP levels from ages 9 to 21, when marked physical and behavioral changes could contribute to growing sex disparities in CRP. ME...

journal_title：Psychoneuroendocrinology

authors： Shanahan L,Copeland WE,Worthman CM,Erkanli A,Angold A,Costello EJ

更新日期：2013-10-01 00:00:00

abstract：:Oxytocin has been shown to affect human social information processing including recognition memory for faces. Here we investigated the neural processes underlying the effect of oxytocin on memorizing own-race and other-race faces in men and women. In a placebo-controlled, double-blind, between-subject study, participa...

journal_title：Psychoneuroendocrinology

authors： Herzmann G,Bird CW,Freeman M,Curran T

更新日期：2013-10-01 00:00:00

abstract：:This study was conducted to clarify the role of serotonin (5-hydroxytryptamine, 5-HT) 2C receptor (5-HT2CR) signaling during novelty-induced hypophagia in aged mice. Male C57BL/6J mice [6-week-old (young) and 79-80-week-old (aged) mice] were exposed to a novel environment, and its effects on feeding behavior, stress h...

journal_title：Psychoneuroendocrinology

authors： Nahata M,Muto S,Nakagawa K,Ohnishi S,Sadakane C,Saegusa Y,Iizuka S,Hattori T,Asaka M,Takeda H

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Depression and anxiety have been suggested to be associated with systemic inflammation upregulation. However, results are not always consistent, which may be due to symptom heterogeneity of depression and anxiety. There are some indications that associations with inflammation are mainly driven by somatic symp...

journal_title：Psychoneuroendocrinology

authors： Duivis HE,Vogelzangs N,Kupper N,de Jonge P,Penninx BW

更新日期：2013-09-01 00:00:00

abstract：:Chronic psychological stress appears to accelerate biological aging, and oxidative damage is an important potential mediator of this process. However, the mechanisms by which psychological stress promotes oxidative damage are poorly understood. This study investigates the theory that cortisol increases in response to ...

journal_title：Psychoneuroendocrinology

authors： Aschbacher K,O'Donovan A,Wolkowitz OM,Dhabhar FS,Su Y,Epel E

更新日期：2013-09-01 00:00:00

abstract：:Intertemporal choices between a smaller sooner and a larger delayed reward are one of the most important types of decisions humans face in their everyday life. The degree to which individuals discount delayed rewards correlates with impulsiveness. Steep delay discounting has been associated with negative outcomes over...

journal_title：Psychoneuroendocrinology

authors： Ortner GR,Wibral M,Becker A,Dohmen T,Klingmüller D,Falk A,Weber B

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:The main aim of this exploratory study was to assess whether salivary α-amylase (sAA) and salivary cortisol levels would be positively modulated by sleep-focused mind-body interventions in female and male cancer survivors. METHODS:We conducted a randomized controlled trial in which 57 cancer survivors with s...

journal_title：Psychoneuroendocrinology

authors： Lipschitz DL,Kuhn R,Kinney AY,Donaldson GW,Nakamura Y

更新日期：2013-09-01 00:00:00

abstract：:In psychiatry, neuroendocrine techniques were initially considered a potential "window into the brain" by indirectly marking central nervous system limbic dysfunction. At present this conception has evolved, owing to significant progress over the last decades demonstrating direct involvement of neuropeptides and neuro...

journal_title：Psychoneuroendocrinology

authors： Duval F,Mokrani MC,Crocq MA

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Little is known of the association between thyroid hormones in the central nervous system and Alzheimer's disease (AD). We determined thyroid hormone levels in serum and cerebrospinal fluid (CSF) in a well-defined homogeneous mono-center population. METHODS:Fifty-nine consecutive patients under primary eval...

journal_title：Psychoneuroendocrinology

authors： Johansson P,Almqvist EG,Johansson JO,Mattsson N,Hansson O,Wallin A,Blennow K,Zetterberg H,Svensson J

更新日期：2013-07-01 00:00:00